Product Description
Brand Eppendorf
Model BioFlo
Capacity 720 L
CAT No. 1385200011
Application Bioprocess
- Compatible with Thermo Scientific HyPerforma 5:1 bioreactors from 50?L to 2,000?L
- High performance Mass Flow Controllers capable of up to 500:1 turn-down allowing multiple bioreactor sizes to be run from the same controller
- Suitable for analog and digital sensors Mettler-ToledoISMand HamiltonARC
- Available with dual sparge, overlay and CO2stripping options
- Field-upgradeable options for future expansion of the system
- Documentation packages available to help qualifying the system for use in GMP environments1)
- Intuitive software tools such as Auto Calibrate and Auto Inflate reduce preparation time, maximizing system efficiency
- Integrated Scale Up Assist software simplifies the workflow and calculations necessary to scale up and scale down
- Flexible choices for single-use bioreactors (SUBs) and Bioprocess Containers (BPCs)
- Mobile enclosure with a small footprint (0.7m2/7.55sq ft) fitting through a standard lab door
- Watson-Marlowperistaltic pumps for flow rates in a range of 1.2mL/min - 3.3L/min
Advanced Process ControlEquipped with automated control of key parameters including pH, DO, temperature, agitation, and aeration, the BioFlo 720 ensures reliable and reproducible bioprocess outcomes. Integrated PID technology and antifoaming features offer a high degree of process flexibility for optimal cell growth and product yield.
Designed for Versatility and ConvenienceSupporting both single-wall and double-wall vessel types, the BioFlo 720 meets a range of temperature and dissolved gas control needs. The 10.4-inch color touchscreen, remote PC compatibility, and SCADA integration provide intuitive, flexible user interaction for laboratory or production environments.
Robust Build and SterilityConstructed from durable stainless steel and high-grade plastics, the BioFlo 720 features in-place sterilization (SIP) for stringent sterility assurance. Its automated controls and integrated alarms enhance user safety and process reliability during critical bioprocess operations.
FAQ's of Eppendorf BioFlo 720:
Q: How does the Eppendorf BioFlo 720 ensure precise control over process parameters?
A: The system provides automated and PID-controlled regulation of pH, dissolved oxygen, temperature (10 C over ambient to 65 C), agitation (up to 700 rpm), aeration, and antifoaming. This precision is monitored via integrated audio/visual alarms and managed through its 10.4-inch color touchscreen or remote SCADA software.
Q: What types of vessel configurations are available, and what are their benefits?
A: The BioFlo 720 offers both single-wall and double-wall vessels, allowing users to select the configuration that best suits their temperature control and heat-transfer needs. Double-wall vessels enhance precise temperature regulation and are suitable for sensitive cell cultures.
Q: When should the in-place sterilization (SIP) feature be used?
A: SIP should be performed before starting any bioprocess to ensure all internal components are sterile, and after concluding a process to prepare the system for its next run, thereby reducing contamination risk and supporting cGMP compliance.
Q: Where is the BioFlo 720 commonly deployed?
A: This system is widely used in laboratory, pilot, and cGMP production environments in India, supporting research organizations, vaccine and protein manufacturers, as well as bioprocessing labs seeking flexible and automated bioreactor solutions.
Q: What is the process for monitoring and adjusting bioreactor operations?
A: Users interact with the system via the large touchscreen interface, remote PC, or connected SCADA software suite. Real-time data logging, alarms, and manual or automated parameter adjustments ensure optimal control throughout the bioprocess.
Q: How does the connectivity of the BioFlo 720 enhance its usage?
A: With Ethernet, USB, and analog/digital I/O ports, along with SCADA software compatibility, the BioFlo 720 enables seamless data transfer, remote operation, and integration into broader process management systems.
Q: What are the main benefits of using the BioFlo 720 for bioprocessing applications?
A: The BioFlo 720 offers robust process control, reliable sterility (via SIP), user-friendly operation, versatile vessel options, comprehensive connectivity, and is designed for demanding applications like mammalian cell culture, microbial fermentation, and vaccine or protein production.