Product Description
Brand Eppendorf
Model BioFlo
Capacity 320 L
CAT No. 1379963011
Application Bioprocess
The BioFlo 320 is a universal benchtop bioreactor system. It is suitable for cell culture as well as fermentation applications and can be used with glass and BioBLUSingle-Use Bioreactors. Powerful technology for precise process monitoring and control, a large working volume range, and software features that save time and reduce risks make it a reliable partner for developing robust processes and moving them from R&D to production.
Versatile Vessel CompatibilityBioFlo 320 supports both single-use and autoclavable glass vessels, giving users the freedom to choose based on process requirements and compliance needs. The system adapts to volume scales from 250 mL up to 10.5 L, making it ideal for a wide range of cell culture and microbial fermentation applications.
Precise Environmental ControlIntegrated heating blankets and cooling fingers maintain optimal temperature regulation for sensitive bioprocesses. Up to four mass flow controllers manage gas input precisely, while magnetically coupled or direct drives provide reliable agitation. Together, these features enable superior consistency and reproducibility in experimental outcomes.
Advanced Monitoring and Data IntegrationWith sensor ports for pH, DO, temperature, foam/level, and off-gas analysis, users benefit from comprehensive process insights. Data logging can be managed via USB, ethernet, or integration with SCADA systems, supporting robust documentation and real-time monitoring both locally and remotely.
FAQ's of Eppendorf BioFlo 320:
Q: How does the Eppendorf BioFlo 320 temperature control system function?
A: The BioFlo 320 utilizes an integrated heating blanket and a cooling finger to maintain set temperatures within the vessel. This combination provides precise and consistent control, which is essential for optimal growth and productivity in cell culture and microbial fermentation processes.
Q: What vessel types and volumes are supported by the BioFlo 320?
A: It supports a range of vessel types, including single-use and autoclavable glass vessels, with working volumes from 250 mL up to 10.5 L. This flexibility accommodates small-scale research as well as larger process development applications.
Q: When should I use single-use vessels versus autoclavable glass vessels?
A: Single-use vessels are ideal for processes requiring rapid turnarounds or when avoiding cross-contamination is critical. Autoclavable glass vessels are preferred for applications needing sterile re-use and complex sampling or instrumentation setups.
Q: Where can I access data from the BioFlo 320 during operation?
A: You can retrieve and monitor data directly via the system's touchscreen interface, through local USB or ethernet connections, or remotely using compatible software with SCADA system integration. This accessibility supports real-time process monitoring and record keeping.
Q: What is the benefit of having customizable control recipes in the system?
A: Customizable digital control recipes allow users to automate and standardize process protocols. This feature maximizes reproducibility, minimizes user error, and saves time by enabling pre-set conditions tailored to specific cell lines or microbes.
Q: How does the BioFlo 320 alert users to critical system states?
A: The system is equipped with both visual and audible alarms for immediate on-site notification. Additionally, it offers remote notifications to ensure users are alerted to deviations or important events even when away from the laboratory.